HISTOLOGICAL STUDIES ON HOG CHOLERA

Studies on the Dissociation of the Hog Cholera Bacillus

1. Heat killed organisms of the MS (OH), MR (ØH), NS (O) or NR (Ø) forms of hog cholera bacilli failed to confer immunity, at least to any considerable degree, in hamsters or rabbits against virulent hog cholera bacilli. 2. Hamsters and rabbits were successfully immunized against virulent MS bacilli by vaccination with living MR (ØH) and NR (Ø) forms. 3. Hamsters were immunized against MS hog c...

Mutation among Hog-cholera Bacilli

1. In the hog-cholera group the mutation from smooth (A) to granular (B) type occurs and a mutant with a moist, opaque colony formation was noted. 2. The B mutant when obtained pure remains a B type without reversion in the stock cultures. 3. The B mutant can be made to assume some of the A characters by rapid successive transplanting in bouillon. 4. The B mutant can usually be found in older t...

Hog cholera virus: art and facts.

The aim of this review is to summarize the informations accumulated during the two last decades on hog cholera virus, a member of the pestivirus genus. Different aspects concerning the virus-host cell interactions, and the structural and antigenic properties of the virion itself are successively analyzed. Despite numerous works, many basic informations are still lacking, which can be explained ...

Cultivation of the Hog Cholera Virus

The work of Hecke on the cultivation, of hog cholera virus was confirmed with ease. Virus was grown in the presence of fresh minced swine testicle in flasks containing Tyrode solution, on the chorioallantoic membrane of embryonated eggs, and on the surface of swine serum agar. In flasks it was grown for 14 transfers; while on eggs it was grown for 13 transfers, followed by an equal number of tr...

Modified Live Virus Hog Cholera Vaccine--M.L.V